Israel’s COVID-19 vaccination prevents the epidemic

Jack Guez / Getty Images

On February 1, a health worker delivered a dose of the Pfizer-Bionatech COVID-19 vaccine in Petah Tikva, Israel.

More than six weeks after the start of Israel COVID-19 There is a vaccine rollout He woke her up and left her behind all over the world, Public health experts sigh of relief that this is finally kicking off.

Earlier this week, as the country reported a clear and sustainable decline in the number of critically ill people aged 60 or older, experts became confident they were seeing the effects of the vaccine. In the early stages of Israel’s vaccine rollout, people over the age of 60 were given priority, so the signal was expected to appear in the National Covid-19 statistics.

“We say carefully, the magic has begun,” Tweeted Iran Segal, a data scientist at the Weizmann Institute of Science in Rehovot, Israel, noted on February 1 that CVD-19 cases, hospitalizations and serious illnesses all fell into the 1990s.

What’s more, follow-up studies conducted by McBee Health Care Services, one of the largest HMOs in Israel, suggest that Pfeiffer’s COVID-19 vaccine, used for most of the shots given so far, is working almost like the real world in clinical trials, two doses. Later with more than 90% effectiveness. This was no guarantee: drugs and vaccines could perform somewhat differently outside the controlled limits of clinical trials.

This is good news for the United States and other countries that hope to emulate Israel’s success in delivering the Covid-19 vaccine to their populations. However, the information raised by Israel also reveals the challenges ahead.

In an interview with BuzzFeed News, Israeli experts hoped that these positive results would show up sooner. They blamed a large part of the delay on the fact that the Middle Eastern nation has been fighting a highly contagious race. B.1.1..7 Coronavirus variant First seen in the UK – now thought to be responsible for more than 70% of cases in Israel and when both Pfizer and Modarna Reported that their vaccines effectively block the B1.1..7 variant, seemingly the first variant identified between South Africa and Brazil Less capable In existing vaccines, however, further progress may be slowed down if new variants become dominant with them or similar mutations.

Meanwhile, human rights groups have been criticized for failing to increase vaccination programs in the Israeli-occupied Palestinian territories. The rollout between Israel’s Palestinian Arabs and the ultra-orthodox Jewish community has slowed – which is worrying because these groups have been hit the hardest by Kovid-19.

Health experts are concerned that the Israeli government is seeing a rollout of Israelis in the United States, despite the Israeli government continuing a large-scale communications effort involving religious and other community leaders to try to diversify the vaccine between Arab and ultra-orthodox communities.

In the United States, black has been American Killing irrelevantly And ill by COVID-19 and ha Already Falling backwards In the US vaccination campaign. And when there are good reasons to distrust the medical institutions offered to black Americans The legacy of racism Peter Hottz, a top vaccine researcher at the Baylor College of Medicine in Houston, said nothing had happened in the U.S. health care system as Israeli contacts pressured skeptical groups to believe in the benefits of vaccination.

Hotez fears a terrible status in the black community if the rollout of the vaccine is low and retains the more dangerous coronavirus form. “We are losing a generation of mothers and fathers, brothers and sisters,” he said.

If we keep the actual rates of vaccine hesitation in the African American community unchanged from the reports we receive from the @ illustrated or @ KFF, it indicates that the new UK, Brazil, and ZA variants will be widespread in the spring: blacks across the Americas.

Twitter: @PeterHotage

Israel deserves a vaccine rollout for a rapid healthcare system in which each citizen must be a member of four HMOs, which operate clinics almost everywhere in small, densely populated countries. With the supply of vaccines protected from both Pfizer and Modarna, the nation was able to move forward with this tougher healthcare infrastructure to vaccinate faster than at any other time: as of Wednesday, Israel has given 59 shots per 100 people In the country, America has given about 10.

The rules for those eligible for the vaccine in Israel were also much simpler than in the United States, where decisions were made in the states based on a variety of factors, including age, occupational exposure to the virus, and pre-treatment conditions. Instead, Israel gave priority to the elderly, encouraged everyone to give shots, and opened call centers to make appointments more readily available. Even with its existing infrastructure, it opens outdoor immunization centers.

“They made it very easy to sign up,” said Anne Blake, a physician and public health instructor in Israel who is a colleague at the hotel in Bellor. “If the vaccine is left at the end of the day, clinic secretaries are blasting text messages to you.”

Israel’s vaccine rollout leads the world

The United States faces a huge challenge with many more fragmented health care systems and Israel’s campaign to vaccinate many people without health insurance. Blake argued that the country needs to learn from what Israel has done, open larger vaccination centers, and simplify vaccination eligibility rules.

“We need to open stadiums across the country,” he said. “It simply came to our notice then. We need to make it bigger. “

However, Israel has been less effective in controlling the spread of the virus. The start of the vaccination campaign on 19 December marked the beginning of a major upheaval in the case of the now influential B1.1..7 variant. On December 2, a nationwide lockdown occurred, making it difficult for scientists to distinguish the protective effects of vaccines from infections that have been reduced by the lockdown.

Uri Shalit, a data scientist at Hyper Technician who specializes in healthcare studies, said: “As all these strong winds are pushed in different directions, it is difficult to detect the effect of the vaccine.

As recently as last week, Shalit and other experts were still worried about the difference in this lockdown trend compared to the previous one, which ended in October. This week, however, it was clear that Israel was seeing a decline in the number of elderly people with acute COVID-19, which began even after serious cases continued among young people.

Israelis with age-based deadly COVID-19

Peter Aldous / BuzzFeed News / Through the Israeli Ministry of Health /

The charts above and below show that, in severe cases, the decline began in mid-January, with a kind of increase in the number of older Israelis receiving a second vaccine shot. Right now, more than -0s have been shot twice in more than a decade, although growth has slowed in recent days – some scientists fear. Computer scientist Yaniv Erlich at the interdisciplinary center Harzalia, which tracks data on COVID-19, told BuzzFeed News that “you made the recipients tired at first.”

Percentage of Israelites have been vaccinated by age

Peter Aldous / BuzzFeed News / Through the Israeli Ministry of Health /

Nevertheless, studies followed by Israeli HMOs are adding to the optimistic picture. Inside A preliminary research paper Posted online January 29, which has not yet been peer-reviewed, researchers at McBee Health Care Services followed them with more than 35,000,000 adults 13-24 days after receiving the first dose of the Pfizer vaccine, estimating it to be 51. % Was effective in preventing infection.

And still unpublished data, The Times of Israel reported last week The MacBee researchers discovered that the vaccine was 92% effective after two meals, based on a comparison of 163,000 fully vaccinated MacBee patients from an undiagnosed group. If these results stand up, it means that the Pfeiffer vaccine is almost performing in the real world This was the case in clinical trials.

Erlich and Others It was warned that these results could lead to excessive review of the effects of the vaccine. One thing is that Israeli couples usually vaccinate together to give extra protection to families which does not happen with volunteers in clinical trials.

But Cyril Cohen, a non-executive and vice-dean of biology at Bar-Ilan University in Ramat Gaan, was pleased with the report. “It equates to the forecast,” he told BuzzFeed News. “I’m always careful, but so far it’s very good news.”

Jafar Ashtieh / Getty Images

A barber works while watching a live television broadcast of the vaccination of Palestinian health workers in the occupied West Bank city of Nablus on February 24th.

With low rates of vaccination in cities of the ultra-Orthodox Jewish community and large Arab-Israeli populations, the less encouraging ging casts doubt on the ultra-Orthodox Jewish vaccine and opposes restrictions to limit the spread of the coronavirus. The presence of thousands of mourners On January 31, a prominent rabbi in Jerusalem protested the country’s current lockdown at a funeral.

And at the end of January, Less than 70% of the over-60s at NASA, Sometimes called the “Arab capital” of Israel, they were given the initial vaccine dose – far behind the national average. Taking small doses of the vaccine in Nazareth and other Israeli cities, including large Arab populations, is thought to be linked to widespread distrust by the Israeli government.

Another controversial issue is the vaccination of Palestinians in the occupied territories. Israel maintains that health is the responsibility of the Palestinian National Authority under the Oslo Accords, which There are reportedly plans to buy 100,000 doses The Sputnik V vaccine, developed by the Gamalia Research Institute in Russia.

Pressured by co-groups Human Rights Watch, Argues that the Fourth Geneva Convention requires Israel to provide medical care, Israel has begun Send a small number of vaccines To the Palestinians. Thousands of Palestinians work in Israel – a regular influx of people at checkpoints The move is also fueled by concerns that the country’s own immunization campaign will suffer.

The gaps in Israel’s vaccine rollout mean that even the world’s top human population will have a component of the COVD-19 vaccine where the coronavirus is still circulating freely. This includes children: The Pfizer vaccine is currently only approved for children 16 years of age or older. “We will not vaccinate children under the age of 16 until we receive the results of Pfizer’s clinical trials,” said Cohen, who sits on a committee advising the Israeli Ministry of Health on the Kozid-19 vaccine clinical trial.

As long as the virus is not circulating, there is a possibility of new forms, some of which may avoid existing vaccines. Both Pfizer and Modern are test options for responding to variants with additional booster shots or completely new vaccine formulations. This, however, means that some social distance measures will necessarily continue, especially if emerging forms exacerbate future coronaviruses.

Haggai Rossman, a researcher with the Segal group at the Weizmann Institute, has expressed concern about the issue, fearing that it will comply with even more stringent sanctions. “People will no longer take a tough lockdown after the vaccination campaign,” Rosen said.

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