“The study examines a lot of what people think,” said Caliop Holingu, a psychiatrist at the Center for Autism and Related Disorders at the Kennedy Krieger Institute in Maryland. Diet “That being said, I don’t think it will completely rule out the possibility that the microbiome may play a role in autism.”
One critique, he says, is that the study focuses on snapshots over a longer period of time. “Although the authors did not find that autism itself was associated with intestinal microbiome composition or diversity, this does not mean that the microbiome was not involved at any time, for example, prior to the study,” Holingu said. Yap acknowledges that in order to evaluate causation, longitudinal studies will be important.
Although no research has been done so far Finally shown This, in turn, is an early indication of a relationship between gut and autism seeds expecting a cure. For example, a research group from Arizona State University published A study in 2017 It took 18 children on the autism spectrum who were suffering from gastrointestinal problems and had their bowel replaced. In 2019, the team released a Two years follow-up, And reported about 50 percent improvement in autism-related symptoms. But the study was not randomized, did not have a control group, was not compared with a placebo, and had a small sample size.
Arizona State University has been a source of controversy within the field of study, Hollingo said. “Some people are big fans of them. And I think some other people are very concerned that they are doing more harm than good, and maybe it’s not clear what the purpose is, “he says. “Many autistic communities have been vocal in saying that they do not want to focus on research into the cure of autism or the treatment of autism, but rather co-occurring situations and the things that support them,” he said.
Despite the lack of specific evidence to support efficacy, preliminary research has treated clinics for autistic people with interventions such as probiotics, prebiotics, and fecal microbiota transplants, or FMTs (or less often, “transpositions”). Stool replacement – where a healthy person’s defecation germs are given to the patient anal or orally – has been shown to benefit certain conditions: in particular, Clostridioides Treatment Of Diffuse Colitis, An often debilitating, sometimes fatal, condition that results from excessive use of antibiotics, upsetting the balance of bacteria in the gut. This success has led to hype surrounding attempts to treat a greater number of conditions – including autism.
“When autistic people or [their] Families are told that anyone with autism is given only zero effective support, “said James Cusack, CEO of Autism, a UK-based autism research charity based in Spectrum. “And it can be a very traumatic experience for families and people with autism.” It also means that a parent may be forced to find alternative ways to ensure that their child develops as well as their peers. (A 2015 study Parents have been surveyed and found that about 9 out of 10 children have looked for complementary and alternative medications for their children’s autism.) These parents may be more sensitive to trying things that are not really evidence-based, Cusak said. “And it’s really sad that people are in this position. All we have to do is try to get people to understand the reasons for these decisions and try to support them in taking a different approach. “